KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2A
All Species:
31.21
Human Site:
T728
Identified Species:
68.67
UniProt:
P24928
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24928
NP_000928.1
1970
217176
T728
H
N
N
E
L
E
P
T
P
G
N
T
L
R
Q
Chimpanzee
Pan troglodytes
XP_511300
1913
211215
T728
H
N
N
E
L
E
P
T
P
G
N
T
L
R
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_858599
1896
209574
T730
H
N
N
E
L
E
P
T
P
G
N
T
L
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
P08775
1970
217158
T728
H
N
N
E
L
E
P
T
P
G
N
T
L
R
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
A318
D
F
L
Q
L
Q
C
A
L
Y
I
N
S
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_682682
1972
217631
T725
H
N
N
E
L
E
P
T
P
G
N
T
L
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P04052
1887
209150
T720
H
N
M
E
L
E
P
T
P
G
N
T
L
R
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P16356
1852
203961
T718
H
N
D
D
L
E
P
T
P
G
N
T
L
R
Q
Sea Urchin
Strong. purpuratus
XP_001176260
1921
212544
T728
H
N
D
E
L
T
P
T
P
G
N
S
L
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P18616
1840
204671
E725
Q
G
K
E
L
D
P
E
P
G
R
T
M
R
D
Baker's Yeast
Sacchar. cerevisiae
P04050
1733
191593
V652
L
F
G
N
I
Q
K
V
V
N
F
W
L
L
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
N.A.
95.9
N.A.
99.9
N.A.
N.A.
N.A.
26.2
N.A.
94.9
N.A.
71.1
N.A.
67.4
77.6
Protein Similarity:
100
96.8
N.A.
96
N.A.
99.9
N.A.
N.A.
N.A.
40.8
N.A.
97.8
N.A.
84.1
N.A.
81
87.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
6.6
N.A.
100
N.A.
93.3
N.A.
86.6
80
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
20
N.A.
100
N.A.
93.3
N.A.
100
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
57.4
50.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.9
64.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
19
10
0
10
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
73
0
64
0
10
0
0
0
0
0
10
0
% E
% Phe:
0
19
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
10
10
0
0
0
0
0
0
82
0
0
0
0
0
% G
% His:
73
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
10
0
91
0
0
0
10
0
0
0
82
10
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
73
46
10
0
0
0
0
0
10
73
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
82
0
82
0
0
0
0
0
0
% P
% Gln:
10
0
0
10
0
19
0
0
0
0
0
0
0
0
73
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
82
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% S
% Thr:
0
0
0
0
0
10
0
73
0
0
0
73
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _